Where an organization and its AI reason together

Mantis builds cognitive infrastructure for the AI-native enterprise: environments where people and AI work over the same data, knowledge, software, and workflows.

Thesis

Cognitive infrastructure for the AI-native enterprise

Mantis is building cognitive infrastructure for the AI-native enterprise: systems that transform an organization’s existing data, knowledge, software, and workflows into environments where humans and AI can reason and act together.

Rather than adding another chatbot or intelligence layer on top of the enterprise, Mantis embeds AI capabilities directly into the systems organizations already use, making complex information more legible, decisions more grounded, and workflows more capable.

The thesis extends Professor Manolis Kellis’s long-standing research philosophy of using computation to reveal hidden structure in complex systems, from genomics and biological circuitry to organizations themselves. Mantis is developed in his group at MIT and CSAIL, where machine learning research sits alongside interface and systems engineering.

Built at

The MIT and CSAIL names identify where Mantis is built. Neither institution endorses the product.

Platform
Cognitive infrastructure: spatial workspace, map engine, and agent runtime
Focus
Making complex information legible, decisions grounded, and workflows more capable
Built at
MIT CSAIL
Designed with
Research groups, core facilities, and data teams working inside the systems they already run
Analysis
Interactive analysis, with no re-indexing
Compute
Runs on your own hardware or on hosted workers

Use cases

Designed for real-world work at scale

  1. Literature review

    Map thousands of papers and documents at once to see the shape of a field before reading any of them.

  2. Scientific data

    Explore single-cell, molecular, and geospatial datasets as maps instead of static, disconnected plots.

  3. Agent-assisted research

    Give AI agents and automated pipelines a native way to investigate the same map your team uses.

  4. Embedded maps

    Build interactive maps, clusters, and filters directly into products and notebooks.

  5. Traceable analysis

    Resolve high-stakes questions across teams with evidence that stays linked to its source.

Connected to the sources you work in

Mantis reads open corpora, institutional archives, and private collections, and maps them into one navigable space.

  • arXiv
  • PubMed
  • Europe PMC
  • NASA
  • USGS
  • GBIF
  • figshare
  • Open Library
  • Wikipedia
  • SEC
  • Art Institute of Chicago
  • OpenAI

Build on Mantis

Mantis provides the infrastructure, integrations, and tooling to bring semantic exploration into production. Start with the docs, or talk to the team about your use case.