Case study · Life sciences
Alzheimer’s disease research since 2000
How has Alzheimer’s research moved between topics over a quarter century?
The Space
Alzheimer's disease research since 2000
41,673 of each year's most cited Alzheimer's disease papers from 2000 to 2026, laid out by what their abstracts say and grouped into 19 research topics, with year, journal, citations and MeSH terms.
Source: Europe PMC (EMBL-EBI) with MEDLINE records (NLM); abstract text kept only for Creative Commons papers.
41,673 records
Largest clusters in the map sample
- Clinical diagnosis, cognition & care18%
- Synapses, models & neuroprotection16%
- Brain imaging (MRI, PET, EEG)11%
- Tau & neuropathology10%
- Genetics & APOE9%
- Fluid biomarkers9%
- Amyloid & immunotherapy8%
- Cholinesterase inhibitors & drug design7%
On the map
What to look for
- Papers are placed by what their abstracts say and grouped into 19 research topics.
- Year, journal, citations and MeSH terms ride along with every paper, so a topic can be read over time.
With Mantis
What to ask
- Which topics grew fastest after 2015?
- Compare amyloid and tau research by citations.
- Which MeSH terms separate biomarker papers from clinical trials?
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